Download Advances in Molecular and Cellular Endocrinology, Vol. 2 by Derek LeRoith PDF

By Derek LeRoith

Quantity 2 has taken with facets of the pituitary gland either anterior (growth hormone and prolactin receptors, and GH motion) and posterior (vasopressin) pituitary. moreover, thyroid melanoma and steroidogenic enzymes and precocious puberty are coated. ultimately, the "hot subject matters" contain leptin and progress issue signaling.

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Extra resources for Advances in Molecular and Cellular Endocrinology, Vol. 2

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Zhao, Z. (1996). Mammalian SH2-containing protein tyrosine phosphatases. Cell 85, 15. A. (1991). A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor. J. Biol. Chem. 266, 20110-20117. , & Ullrich, A. (1996). PTP1D is a positive regulator of the prolactin signal leading to 13-casein promoter activation. EMBO J. 15, 135-142. , & Carter-Su, C. (1993). Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell 74, 237-244. , & Carter-Su, C.

Mol. Endocrinol. 9, 303-311. A. (1994). Structural and functional basis for hormone binding and receptor oligomerization. Curr. Opin. Cell. Biol. 6, 163-173. A. (1996). Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. USA 93, 1-6. A. (1995). Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/STAT5. J. Biol. Chem. 270, 9448-9453. This Page Intentionally Left Blank Chapter 2 Molecular Aspects of Growth Hormone Action MICHAEL J. THOMAS and PETER ROTWEIN Introduction Growth Hormone: Structure Growth Hormone Receptor Structure and Expression Ligand Binding and Dimerization Growth Hormone Receptor Signaling Activation of JAK2 Phosphorylation and Activation of Intracellular Proteins Activation of STATs Activation of Gene Expression by Growth Hormone Growth Hormone Receptor Internalization and Translocation to the Nucleus Other Signal Transduction Pathways Activated by Growth Hormone Specificity of Signaling by the Growth Hormone Receptor Summary Acknowledgments Advances in Molecular and Cellular Endocrinology Volume 2, pages 35-57.

Science 268, 251-255. M. (1995). Activation of Stat factors by prolactin, interferon-y, growth hormones, and a tyrosine phosphatase inhibitor in rabbit primary mammary epithelial cells. J. Biol. Chem. 270, 20952-20961. , & Carter-Su, C. (1995a). Growth hormone -promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2. J. Biol. Chem. 270, 7587-7593. , & Carter-Su, C. (1995b). Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor.

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